Components that help in anthelmintic action are substances that can contribute to eliminating or inhibiting intestinal parasites. Here are some examples
The anthelmintic drugs fight against nematodes, gastrointestinal parasites. Albendazole, fenbendazole, mebendazole, oxibendazole, parbendazole , flubendazole belong to the family of benzimidazole and exercise anthelmintic activity.
- Piperazine. Used to treat infections by roundworms and pinworms.
- Ivermectin. Effective against various parasites, including some types of worms and mites.
- Pyrantel Pamoate. Used to treat infections by pinworms, roundworms, and other nematodes.
- Garlic. Has natural antiparasitic properties and can be effective against some types of intestinal worms.
- Pumpkin Seeds. Traditionally used to eliminate intestinal worms due to their vermifuge properties.
- Wormwood. An herb with antiparasitic properties, often used in natural preparations against worms.
- Neem Oil. Known for its antiparasitic properties, it can be used against various parasites.
- Papaya and Papaya Seeds. Contain enzymes that can help eliminate intestinal parasites.
- Turmeric. Has anti-inflammatory and antimicrobial properties that can aid in fighting parasites.
The reports provided on Tiiips website are for informational purposes only and should not replace medical advice. Always consult a healthcare professional before making health-related decisions.
Components that can contribute to or exacerbate helminthic infections include various factors that can increase the risk of worm infestations. Here are some examples
- Contaminated Water. Drinking or coming into contact with water contaminated with worm eggs or larvae can lead to infections.
- Poor Hygiene. Lack of personal hygiene, such as inadequate handwashing, can increase the risk of worm transmission.
- Consumption of Raw or Undercooked Meat. Raw or undercooked meat, especially pork or fish, can contain worm larvae.
- Contact with Contaminated Soil. Walking barefoot on contaminated ground can expose to worm infections that penetrate through the skin.
- Overcrowded Living Conditions. Crowded environments can facilitate the transmission of worms, especially in areas with poor sanitation.
- Travel to High-Risk Areas. Traveling to regions with a high prevalence of helminthic infections can increase the risk of exposure.
- Contact with Infected Animals. Pets or farm animals can be carriers of worms and transmit them to humans.
- Consumption of Contaminated Food. Food contaminated with worm eggs or larvae can cause infections.
- Lack of Adequate Water Filters. Drinking unfiltered or untreated water in at-risk areas can lead to worm infections.
- Use of Natural Fertilizers. The use of untreated manure or natural fertilizers can contaminate soil and crops with worm eggs.
Studies
In Vitro Anthelmintic Activity of Saponins from Medicago spp. Against Sheep Gastrointestinal Nematodes. Maestrini M, Tava A, Mancini S, Tedesco D, Perrucci S. Molecules. 2020 Jan 7;25(2). pii: E242. doi: 10.3390/molecules25020242
Anthelmintics in the future: current trends in the discovery and development of new drugs against gastrointestinal nematodes. Zajíčková M, Nguyen LT, Skálová L, Raisová Stuchlíková L, Matoušková P. Drug Discov Today. 2019 Dec 26. pii: S1359-6446(19)30466-0. doi: 10.1016/j.drudis.2019.12.007.
Effects of cholesterol content on activity of P-glycoproteins and membrane physical state, and consequences for anthelmintic resistance in the nematode Haemonchus contortus. Riou M, Guégnard F, Le Vern Y, Grasseau I, Koch C, Blesbois E, Kerboeuf D. Parasite. 2020;27:3. doi: 10.1051/parasite/2019079.
Schistosomiasis and hookworm infection in humans: Disease burden, pathobiology and anthelmintic vaccines. Anisuzzaman, Tsuji N. Parasitol Int. 2020 Jan 3;75:102051. doi: 10.1016/j.parint.2020.102051.
The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer. Florio R, Veschi S, di Giacomo V, Pagotto S, Carradori S, Verginelli F, Cirilli R, Casulli A, Grassadonia A, Tinari N, Cataldi A, Amoroso R, Cama A, De Lellis L. Cancers (Basel). 2019 Dec 17;11(12). pii: E2042. doi: 10.3390/cancers11122042.
