Shark liver oil

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Shark liver oil

Evaluation	Evaluation	N. Experts
1	6
2	7
3	8	1
4	9
5	10

Pros:

Possible anti-cancer (1) Cardioprotective (1) Wound-healing (1) Skin protective (1)



<1 / 1>from A_Partyns

Shark liver oil is extracted from different species of sharks: Echinorhinus brucus, Centrophorus squamosus, Isistius brasiliensis, Etmopterus spinax, Etmopterus molleri, etc.This oil contains glycerolipids Alkyl-ether-lipids (AEL) which have a long fatty alkyl chain connected to the glycerol unit. AEL exerts stimulating activity on the immune syste... (Read the full Tiiip)

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"Shark liver oil studies" about Shark liver oil Review Consensus 16
by A_Partyns (12948 pt)

2020-Aug-28 17:52

Shark liver oil studies Evaluation of squalene oxidation mechanisms in human skin surface lipids and shark liver oil supplements.Shimizu N, Ito J, Kato S, Eitsuka T, Saito T, Nishida H, Miyazawa T, N ...

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Shark liver oil studies

Evaluation of squalene oxidation mechanisms in human skin surface lipids and shark liver oil supplements.
Shimizu N, Ito J, Kato S, Eitsuka T, Saito T, Nishida H, Miyazawa T, Nakagawa K.
Ann N Y Acad Sci. 2019 Aug 26. doi: 10.1111/nyas.14219

Dioxin concentrations in dietary supplements containing animal oil on the Japanese market between 2007 and 2014.
Tsutsumi T, Takatsuki S, Teshima R, Matsuda R, Watanabe T, Akiyama H.
Chemosphere. 2018 Jan;191:514-519. doi: 10.1016/j.chemosphere.2017.10.046.

Vascular effects and safety of supplementation with shark liver oil in middle-aged and elderly males.
Hamadate N, Matsumoto Y, Seto K, Yamamoto T, Yamaguchi H, Nakagawa T, Yamamoto E, Fukagawa M, Yazawa K.
Exp Ther Med. 2015 Aug;10(2):641-646.

Jurassic surgery and immunity enhancement by alkyglycerols of shark liver oil.
Palmieri B, Pennelli A, Di Cerbo A.
Lipids Health Dis. 2014 Nov 27;13:178. doi: 10.1186/1476-511X-13-178.

Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. Molina S, Moran-Valero MI, Martin D, Vázquez L, Vargas T, Torres CF, Ramirez de Molina A, Reglero G. Chem Phys Lipids. 2013 Oct-Nov;175-176:50-6. doi: 10.1016/j.chemphyslip.2013.07.011.

Studies on the genotoxic effects of crude liver oils from 3 species of Mediterranean sharks by means of in vitro micronucleus test using human lymphocytes]. Bartfai E, Orsière T, Duffaud F, Villani P, Pompili J, Botta A. Ann Biol Clin (Paris). 2000 Sep-Oct;58(5):595-600.

Antitumor and anti-cachectic effects of shark liver oil and fish oil: comparison between independent or associative chronic supplementation in Walker 256 tumor-bearing rats. Iagher F, de Brito Belo SR, Souza WM, Nunes JR, Naliwaiko K, Sassaki GL, Bonatto SJ, de Oliveira HH, Brito GA, de Lima C, Kryczyk M, de Souza CF, Steffani JA, Nunes EA, Fernandes LC. Lipids Health Dis. 2013 Oct 16;12:146. doi: 10.1186/1476-511X-12-146.

Chronic supplementation with shark liver oil for reducing tumor growth and cachexia in walker 256 tumor-bearing rats. Iagher F, de Brito Belo SR, Naliwaiko K, Franzói AM, de Brito GA, Yamazaki RK, Muritiba AL, Muehlmann LA, Steffani JA, Fernandes LC. Nutr Cancer. 2011 Nov;63(8):1307-15. doi: 10.1080/01635581.2011.607540.

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"Descrizione" about Shark liver oil Review Consensus 8
by A_Partyns (12948 pt)

2019-Nov-06 18:40

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Shark liver oil is extracted from different species of sharks: Echinorhinus brucus, Centrophorus squamosus, Isistius brasiliensis, Etmopterus spinax, Etmopterus molleri, etc.

This oil contains glycerolipids Alkyl-ether-lipids (AEL) which have a long fatty alkyl chain connected to the glycerol unit. AEL exerts stimulating activity on the immune system (1) and anti-tumor activity (2), wound healing activities (3), dermatitis (4)

Echinorhinus brucus liver oil contains squalene (35%), docosahexaenoic acid (18%), eicosapentaenoic acid (18%), palmitic acid (15%), oleic acid (12%), stearic acid (8%), as well as vitamin A (17.08 mg/100 g), vitamin D (15.04 mg/100 g), vitamin K (11.45 mg/100 g) (5).

The most abundant component, squalene, triterpene, is structurally similar to beta-carotene, coenzyme Q10 and vitamins A, K and E and performs cardio-protective action (6).

Shark liver oil studies

References______________________________

(1) Effects of dietary alkylglycerols in lactating rats on immune responses in pups. Oh SY, Jadhav LS. Pediatr Res. 1994 Sep;36(3):300-5.

(2) Natural alkylglycerols restrain growth and metastasis of grafted tumors in mice. Pedrono F, Martin B, Leduc C, Le Lan J, Saïag B, Legrand P, Moulinoux JP, Legrand AB. Nutr Cancer. 2004;48(1):64-9.

(3) An update on the therapeutic role of alkylglycerols. Iannitti T, Palmieri B. Mar Drugs. 2010 Aug 5;8(8):2267-300. doi: 10.3390/md8082267.

(4) Shark liver oil as a supporting therapy in atopic dermatitis. Nowicki R, Barańska-Rybak W. Pol Merkur Lekarski. 2007 Apr;22(130):312-3.

(5) Biochemical Characterization of Liver Oil of Echinorhinus brucus (Bramble Shark) and Its Cytotoxic Evaluation on Neuroblastoma Cell Lines (SHSY-5Y). Venugopal V, Kumaran AK, Sekhar Chatterjee N, Kumar S, Kavilakath S, Nair JR, Mathew S. Scientifica (Cairo). 2016;2016:6294030. doi: 10.1155/2016/6294030.

(6) Squalene: A natural triterpene for use in disease management and therapy. Reddy LH, Couvreur P. Adv Drug Deliv Rev. 2009 Dec 17;61(15):1412-26. doi: 10.1016/j.addr.2009.09.005.