The most significant studies on squalene with reference to intake, properties, phytochemistry.
Evaluation of squalene oxidation mechanisms in human skin surface lipids and shark liver oil supplements.
Shimizu N, Ito J, Kato S, Eitsuka T, Saito T, Nishida H, Miyazawa T, Nakagawa K.
Ann N Y Acad Sci. 2019 Aug 26. doi: 10.1111/nyas.14219.
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice.
Sakul A, Ozansoy M, Elibol B, Ayla Ş, Günal MY, Yozgat Y, Başağa H, Şahin K, Kazancioğlu R, Kiliç Ü.
Turk J Biol. 2019 Jun 13;43(3):179-188. doi: 10.3906/biy-1902-77
Modulation of the neurotransmitter systems through the anti-inflammatory and antidepressant-like effects of squalene from Aurantiochytrium sp.
Sasaki K, Othman MB, Ferdousi F, Yoshida M, Watanabe M, Tominaga K, Isoda H.
PLoS One. 2019 Jun 28;14(6):e0218923. doi: 10.1371/journal.pone.0218923.
Aspergillus flavus squalene synthase as an antifungal target: Expression, activity, and inhibition. Song J, Shang N, Baig N, Yao J, Shin C, Kim BK, Li Q, Malwal SR, Oldfield E, Feng X, Guo RT. Biochem Biophys Res Commun. 2019 May 7;512(3):517-523. doi: 10.1016/j.bbrc.2019.03.070.
The shape of human squalene epoxidase expands the arsenal against cancer. Brown AJ, Chua NK, Yan N. Nat Commun. 2019 Feb 21;10(1):888. doi: 10.1038/s41467-019-08866-y.
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Garcia-Bermudez J, Baudrier L, Bayraktar EC, Shen Y, La K, Guarecuco R, Yucel B, Fiore D, Tavora B, Freinkman E, Chan SH, Lewis C, Min W, Inghirami G, Sabatini DM, Birsoy K.
Nature. 2019 Mar;567(7746):118-122. doi: 10.1038/s41586-019-0945-5
Squalene is a potential endocrine modulator in rat: A proof-of-principle study with 3-methylcholanthrene-induced toxicity.
Suriyakalaa U, Ramachandran R, Usha K, Sankarganesh D, Praveenkumar D, Abinaya S, Tirupathi Pichiah PB, Kamalakkannan S, Achiraman S.
Andrologia. 2018 Dec;50(10):e13117. doi: 10.1111/and.13117.
Current Insights into the Biological Action of Squalene. Lou-Bonafonte JM, Martínez-Beamonte R, Sanclemente T, Surra JC, Herrera-Marcos LV, Sanchez-Marco J, Arnal C, Osada J. Mol Nutr Food Res. 2018 Jun 8:e1800136. doi: 10.1002/mnfr.201800136.
Squalene-PEG-Exendin as High-Affinity Constructs for Pancreatic Beta-Cells. Babič A, Vinet L, Chellakudam V, Janikowska K, Allémann E, Lange N. Bioconjug Chem. 2018 Aug 15;29(8):2531-2540. doi: 10.1021/acs.bioconjchem.8b00186.
Squalene epoxidase as a promising metabolic target in cancer treatment. Cirmena G, Franceschelli P, Isnaldi E, Ferrando L, De Mariano M, Ballestrero A, Zoppoli G. Cancer Lett. 2018 Jul 1;425:13-20. doi: 10.1016/j.canlet.2018.03.034.
Advances in Biochemistry and Microbial Production of Squalene and Its Derivatives. Ghimire GP, Thuan NH, Koirala N, Sohng JK. J Microbiol Biotechnol. 2016 Mar;26(3):441-51. doi: 10.4014/jmb.1510.10039.