Ammonium methacrylate is a chemical compound, antibacterial agent, and polymerizable monomer that is used in experimental and commercial dental restorative materials.
It is commonly found as an excipient in medicinal tablets.
Molecular Formula: C4H9NO2
Molecular Weight: 103.12 g/mol
CAS: 16325-47-6
UNII J2243103QO
EC Number: 240-402-5 608-549-3
DSSTox Substance ID: DTXSID0023874
Synonimys
- ammonium 2-methylacrylate
- Ammonium methacrylate homopolymer
- Ammonium methacrylate polymer
- 2-Propenoic acid, 2-methyl-, ammonium salt, homopolymer
- 2-Propenoic acid, 2-methyl-, ammonium salt (1:1), homopolymer
- 2-Propenoic acid, 2-methyl-, ammonium salt
References______________________________________________________________
Chen L, Suh BI, Yang J. Antibacterial dental restorative materials: A review. Am J Dent. 2018 Nov 15;31(Sp Is B):6B-12B.
Farah S, Aviv O, Laout N, Ratner S, Beyth N, Domb AJ. Quaternary ammonium poly(diethylaminoethyl methacrylate) possessing antimicrobial activity. Colloids Surf B Biointerfaces. 2015 Apr 1;128:608-613. doi: 10.1016/j.colsurfb.2015.01.051.
Okeke UC, Snyder CR, Frukhtbeyn SA. Synthesis, Purification and Characterization of Polymerizable Multifunctional Quaternary Ammonium Compounds. Molecules. 2019 Apr 13;24(8):1464. doi: 10.3390/molecules24081464.
Quaroni GMG, Gennari CGM, Cilurzo F, Ducouret G, Creton C, Minghetti P. Tuning the rheological properties of an ammonium methacrylate copolymer for the design of adhesives suitable for transdermal patches. Eur J Pharm Sci. 2018 Jan 1;111:238-246. doi: 10.1016/j.ejps.2017.10.006.
Makvandi P, Ghaemy M, Ghadiri AA, Mohseni M. Photocurable, Antimicrobial Quaternary Ammonium-modified Nanosilica. J Dent Res. 2015 Oct;94(10):1401-7. doi: 10.1177/0022034515599973.
Kumar Tiwari S, Guo X, Huang Y, Zhou X, Xu HHK, Ren B, Peng X, Weir MD, Li M, Cheng L. The inhibitory effect of quaternary ammonium salt on bacteria in root canal. Sci Rep. 2019 Aug 28;9(1):12463. doi: 10.1038/s41598-019-48666-4.
Pupo YM, Farago PV, Nadal JM, Esmerino LA, Maluf DF, Zawadzki SF, Michél MD, dos Santos FA, Gomes OM, Gomes JC. An innovative quaternary ammonium methacrylate polymer can provide improved antimicrobial properties for a dental adhesive system. J Biomater Sci Polym Ed. 2013;24(12):1443-58. doi: 10.1080/09205063.2013.766784.
Zhou Y, Wang S, Zhou X, Zou Y, Li M, Peng X, Ren B, Xu HHK, Weir MD, Cheng L, Chen Y, Han Q. Short-Time Antibacterial Effects of Dimethylaminododecyl Methacrylate on Oral Multispecies Biofilm In Vitro. Biomed Res Int. 2019 Jan 21;2019:6393470. doi: 10.1155/2019/6393470.
Campos KPL, Viana GM, Cabral LM, Portela MB, Hirata Junior R, Cavalcante LM, Lourenço EJV, Telles DM. Self-cured resin modified by quaternary ammonium methacrylates and chlorhexidine: Cytotoxicity, antimicrobial, physical, and mechanical properties. Dent Mater. 2020 Jan;36(1):68-75. doi: 10.1016/j.dental.2019.10.007.
Zafar N, Bitar A, Valour JP, Fessi H, Elaissari A. Elaboration of ammonio methacrylate copolymer based spongy cationic particles via double emulsion solvent evaporation process. Mater Sci Eng C Mater Biol Appl. 2016 Apr 1;61:85-96. doi: 10.1016/j.msec.2015.12.017.
Hoshika T, Nishitani Y, Yoshiyama M, Key WO 3rd, Brantley W, Agee KA, Breschi L, Cadenaro M, Tay FR, Rueggeberg F, Pashley DH. Effects of quaternary ammonium-methacrylates on the mechanical properties of unfilled resins. Dent Mater. 2014 Nov;30(11):1213-23. doi: 10.1016/j.dental.2014.08.365.
Ammonium methacrylate 
