Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity.
Wang YK, Yang XN, Zhu X, Xiao XR, Yang XW, Qin HB, Gonzalez FJ, Li F.
J Agric Food Chem. 2019 Jul 16. doi: 10.1021/acs.jafc.9b02137.

A comparative study of nutmeg (Myristica fragrans Houtt.) oleoresins obtained by conventional and green extraction techniques.
Morsy NF.
J Food Sci Technol. 2016 Oct;53(10):3770-3777. doi: 10.1007/s13197-016-2363-0.

Physiologically based kinetic models for the alkenylbenzene elemicin in rat and human and possible implications for risk assessment.
van den Berg SJ, Punt A, Soffers AE, Vervoort J, Ngeleja S, Spenkelink B, Rietjens IM.
Chem Res Toxicol. 2012 Nov 19;25(11):2352-67. doi: 10.1021/tx300239z

(E)-Methylisoeugenol and elemicin: antibacterial components of Daucus carota L. essential oil against Campylobacter jejuni.
Rossi PG, Bao L, Luciani A, Panighi J, Desjobert JM, Costa J, Casanova J, Bolla JM, Berti L.
J Agric Food Chem. 2007 Sep 5;55(18):7332-6.

Abuse of nutmeg (Myristica fragrans Houtt.): studies on the metabolism and the toxicologic detection of its ingredients elemicin, myristicin, and safrole in rat and human urine using gas chromatography/mass spectrometry.
Beyer J, Ehlers D, Maurer HH.
Ther Drug Monit. 2006 Aug;28(4):568-75.

Constituents of aromatic plants: elemicin.
De Vincenzi M, De Vincenzi A, Silano M.
Fitoterapia. 2004 Sep;75(6):615-8.

Metabolism of alkenebenzene derivatives in the rat. III. Elemicin and isoelemicin.
Solheim E, Scheline RR.
Xenobiotica. 1980 May;10(5):371-80.

Elemi oil is made from a 30-meter-high tropical tree growing in the Philippines.

In addition to an essential oil, it is a resin and has a pungent smell.

It was used by the ancient Egyptians in embalming processes.

Today it is used in cosmetics as perfume.

In pharmaceuticals it is used for skin care, to stimulate breathing.

Among the components of this oil is Elemicin, an aromatic alkenylbenzene constituent that is also found in the most widespread nutmeg (Myristica fragrans Houtt.) and which has psychoactive properties.

Elemicin studies