A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.).
McKay DL, Blumberg JB.
Phytother Res. 2006 Aug;20(8):619-33.

Peppermint (Mentha piperita L.) extract effectively inhibits cytochrome P450 3A4 (CYP3A4) mRNA induction in rifampicin-treated HepG2 cells.
Kobayashi T, Sugaya K, Onose JI, Abe N.
Biosci Biotechnol Biochem. 2019 Jul;83(7):1181-1192. doi: 10.1080/09168451.2019.1608802.

Mentha piperita L. essential oil inactivates spoilage yeasts in fruit juices through the perturbation of different physiological functions in yeast cells.
Almeida ETDC, de Souza GT, de Sousa Guedes JP, Barbosa IM, de Sousa CP, Castellano LRC, Magnani M, de Souza EL.
Food Microbiol. 2019 Sep;82:20-29. doi: 10.1016/j.fm.2019.01.023.

Toxicity, antifeedant and biochemical efficacy of Mentha piperita L. essential oil and their major constituents against stored grain pest.
Rajkumar V, Gunasekaran C, Christy IK, Dharmaraj J, Chinnaraj P, Paul CA.
Pestic Biochem Physiol. 2019 May;156:138-144. doi: 10.1016/j.pestbp.2019.02.016.

Characterisation of peppermint (Mentha piperita L.) essential oil encapsulates.
Yilmaztekin M, Lević S, Kalušević A, Cam M, Bugarski B, Rakić V, Pavlović V, Nedović V.
J Microencapsul. 2019 Mar;36(2):109-119. doi: 10.1080/02652048.2019.1607596.

Chemical Composition and in vivo Efficacy of the Essential Oil of Mentha piperita L. in the Suppression of Crown Gall Disease on Tomato Plants.
Hsouna AB, Touj N, Hammami I, Dridi K, Al-Ayed AS, Hamdi N.
J Oleo Sci. 2019 May 1;68(5):419-426. doi: 10.5650/jos.ess18261.

Mentha piperita essential oils loaded in a chitosan nanogel with inhibitory effect on biofilm formation against S. mutans on the dental surface.
Ashrafi B, Rashidipour M, Marzban A, Soroush S, Azadpour M, Delfani S, Ramak P.
Carbohydr Polym. 2019 May 15;212:142-149. doi: 10.1016/j.carbpol.2019.02.018.

Effectiveness of Mentha piperita Leaf Extracts against Oral Pathogens: An in vitro Study.
Raghavan R, Devi MPS, Varghese M, Joseph A, Madhavan SS, Sreedevi PV.
J Contemp Dent Pract. 2018 Sep 1;19(9):1042-1046.

Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials.
Rosato A, Carocci A, Catalano A, Clodoveo ML, Franchini C, Corbo F, Carbonara GG, Carrieri A, Fracchiolla G.
PLoS One. 2018 Aug 1;13(8):e0200902. doi: 10.1371/journal.pone.0200902.

Effect of Heat Stress on Yield, Monoterpene Content and Antibacterial Activity of Essential Oils of Mentha x piperita var. Mitcham and Mentha arvensis var. piperascens.
Heydari M, Zanfardino A, Taleei A, Bushehri AAS, Hadian J, Maresca V, Sorbo S, Napoli MD, Varcamonti M, Basile A, Rigano D.
Molecules. 2018 Jul 30;23(8). pii: E1903. doi: 10.3390/molecules23081903.

Antifibrogenic Influence of Mentha piperita L. Essential Oil against CCl4-Induced Liver Fibrosis in Rats.
Ogaly HA, Eltablawy NA, Abd-Elsalam RM.
Oxid Med Cell Longev. 2018 Apr 19;2018:4039753. doi: 10.1155/2018/4039753

The genus Mentha includes about 40 species, 15 hybrids and hundreds of cultivars of plants of this genus belonging to the Lamiaceae family.

Mentha genus is  divided in:

• Audibertia
• Eriodontes
• Mentha
• Preslia
• Pulegium

Most are perennial sunplants and native to Europe, grown in the USA, Canada, Europe, Asia, Australia and South America.

Mint contain essential oils and is widely used as an aroma in drinks, foods and cigarettes.

From an economic point of view the most important species are:

• Mentha aquatica L.
• Mentha canadensis L.
• Mentha spicata L. (spearmint) and their hybrids ( Mentha - piperita L. peppermint)

The typical flavor of mint is due to menthol, an alcoholic terpene and carvone, a terpene ketone.

Mint leaves are used as tea against digestive disorders, headaches.

                                    ________________________

Mentha piperita (peppermint) is a hybrid mint and grows in temperate areas and is utilized by the cosmetic, pharmaceutical and food industries.

It is native to Europe, USA, Canada and is intensively cultivated all over the world for its particular perfume and taste and has been used by traditional medicine to treat cramps, nausea, indigestion.In particular, it is utilized in the form of essential oil (extracted by steam distillation from the aerial parts) and extracts.

It contains some useful components for human health, phenolic acids and flavonoids: rosmarinic acid, quercetin, gallic acid, components known for their antimicrobial  (1), antioxidant (2) and antifungal action (3).

This study explored the antibacterial activities of a mentha piperita extract and concluded that the polyphenol content demonstrated bacteriostatic properties and antiadhesive activity against strains of bacteria of the genus Asaia (a contaminant of industrial beverages) confirming its total antioxidant activity (4).

Another special feature of the healing properties of this mint is the improvement in the wound healings treated with topical application of essential oil (5).

For more information:        Mentha piperita studies

References___________________________________________________________

(1) Seyedeh Maryam Sharafi, Iraj Rasooli, Parviz Owlia, Massoud Taghizadeh, and Shakiba Darvish Alipoor Astaneh Protective effects of bioactive phytochemicals from Mentha piperita with multiple health potentials   Pharmacogn Mag. 2010 Jul-Sep; 6(23): 147–153. doi: 10.4103/0973-1296.66926

(2) Ravindra M.Samarth, Meenakshi Panwar, Manish Kumar, Anil Soni, Madhu Kumar, Ashok Kumar Evaluation of antioxidant and radical-scavenging activities of certain radioprotective plant extracts   Food chemistry, 2008 - Elsevier

(3) Mafakheri H, Mirghazanfari SM Antifungal activity of the essential oils of some medicinal plants against human and plant fungal pathogens.  . Cell Mol Biol (Noisy-le-grand). 2018 Dec 31;64(15):13-19.

(4) Antolak H, Czyżowska A, Kręgiel D. Activity of Mentha piperita L. Ethanol Extract against Acetic Acid Bacteria Asaia spp.    Foods. 2018 Oct 18;7(10). pii: E171. doi: 10.3390/foods7100171.

(5) Modarresi M, Farahpour MR, Baradaran B. Topical application of Mentha piperita essential oil accelerates wound healing in infected mice model.   Inflammopharmacology. 2019 Jun;27(3):531-537. doi: 10.1007/s10787-018-0510-0.