Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial.
Samaha AA, Fawaz M, Salami A, Baydoun S, Eid AH.
Biomolecules. 2019 Jul 20;9(7). pii: E292. doi: 10.3390/biom9070292

Mentha longifolia alleviates experimentally induced angina via decreasing cardiac load.
Azhar AS, El-Bassossy HM, Abdallah HM.
J Food Biochem. 2019 Feb;43(2):e12702. doi: 10.1111/jfbc.12702.

Investigation of the Antibiofilm Effects of Mentha longifolia Essential Oil on Titanium and Stainless Steel Orthopedic Implant Surfaces.
Pazarci O, Tutar U, Kilinc S.
Eurasian J Med. 2019 Jun;51(2):128-132. doi: 10.5152/eurasianjmed.2019.18432

Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Ancient and Conventional Medicine.
Moini Jazani A, Hamdi K, Tansaz M, Nazemiyeh H, Sadeghi Bazargani H, Fazljou SMB, Nasimi Doost Azgomi R.
Biomed Res Int. 2018 Mar 18;2018:3052768. doi: 10.1155/2018/3052768

How the morphological properties of Mentha longifolia.(L.) Huds. may be affected by geographical differences.
Mohammadi M, Asadi-Gharneh HA.
J Photochem Photobiol B. 2018 Jan;178:237-242. doi: 10.1016/j.jphotobiol.2017.10.032.

Mentha longifolia protects against acetic-acid induced colitis in rats.
Murad HA, Abdallah HM, Ali SS.
J Ethnopharmacol. 2016 Aug 22;190:354-61. doi: 10.1016/j.jep.2016.06.016

Antimutagenic and anticancer activity of Al Madinah Alhasawy mint (Mentha longifolia) leaves extract.
Al-Ali K, Abdelrazik M, Alghaithy A, Diab A, El-Beshbishy H, Baghdadi H.
Pak J Biol Sci. 2014 Dec;17(12):1231-6.

Antidiarrheal activity and acute oral toxicity of Mentha longifolia L. essential oil.
Jalilzadeh-Amin G, Maham M.
Avicenna J Phytomed. 2015 Mar-Apr;5(2):128-37.

Phenolic content, antioxidant and astroprotective response to oxidative stress of ethanolic extracts of Mentha longifolia from Sinai.
Eissa TF, González-Burgos E, Carretero ME, Gómez-Serranillos MP.
Nat Prod Commun. 2014 Oct;9(10):1479-82.

Two antigenotoxic chalcone glycosides from Mentha longifolia subsp. longifolia.
Guvenalp Z, Ozbek H, Karadayi M, Gulluce M, Kuruuzum-Uz A, Salih B, Demirezer O.
Pharm Biol. 2015 Jun;53(6):888-96. doi: 10.3109/13880209.2014.948633.

Antibacterial activity of ethyl acetate and aqueous extracts of Mentha longifolia L. and hydroalcoholic extract of Zataria multiflora Boiss. plants against important human pathogens.
Saeidi S, Hassanpour K, Ghamgosha M, Heiat M, Taheri RA, Mirhosseini A, Farnoosh G.
Asian Pac J Trop Med. 2014 Sep;7S1:S186-9. doi: 10.1016/S1995-7645(14)60229-7.

The genus Mentha includes about 40 species, 15 hybrids and hundreds of cultivars of plants of this genus belonging to the Lamiaceae family.

Mentha genus is  divided in:

• Audibertia
• Eriodontes
• Mentha
• Preslia
• Pulegium

Most are perennial sunplants and native to Europe, grown in the USA, Canada, Europe, Asia, Australia and South America.

Mint contain essential oils and is widely used as an aroma in drinks, foods and cigarettes.

From an economic point of view the most important species are:

• Mentha aquatica L.
• Mentha canadensis L.
• Mentha spicata L. (spearmint) and their hybrids ( Mentha - piperita L. peppermint)

The typical flavor of mint is due to menthol, an alcoholic terpene and carvone, a terpene ketone.

Mint leaves are used as tea against digestive disorders, headaches.

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In traditional medicine leaves, bark, seeds, flowers and stem of the Mentha longifolia have been used against digestive disorders and for the care of the respiratory system.

More recently, it has been used mainly by the pharmaceutical, food and cosmetics industries.

This study confirms the synergistic anti-inflammatory activity through a protective mechanism of essential oils of Mentha longifolia (1).

In particular, examination of some interesting components of the essentid oil of this seedling, butanol, methanol, dichloromethane, hexane and ethyl acetate extracts, have made it possible to understand the mechanisms underlying the anti-inflammatory and immunomodulatory effects of this plant (2).

It should be noted, however, that due to the different soil composition, cultivation and climatic conditions, the content of this plant may differ in quality and quantity.

Mentha longifolia studies

References_____________________________________________________________

(1) Synergistic effects of deuterium depleted water and Mentha longifolia L. essential oils on sepsis-induced liver injuries through regulation of cyclooxygenase-2.  Rasooli A, Fatemi F, Hajihosseini R, Vaziri A, Akbarzadeh K, Mohammadi Malayeri MR, Dini S, Foroutanrad M.  Pharm Biol. 2019 Dec;57(1):125-132.

(2) Modulation of in vitro proliferation and cytokine secretion of human lymphocytes by Mentha longifolia extracts.  Asemani Y, BayaT M, Malek-Hosseini S, Amirghofran Z.  Avicenna J Phytomed. 2019 Jan-Feb;9(1):34-43.