Compendium of the most significant studies with reference to properties, intake, effects.

Matsuoka, K., Noshiro, N., Kuroki, H., Tsuyuzaki, K., & Hashimoto, G. (2022). Vesicle formation of disodium lauryl sulfosuccinate. Journal of Molecular Liquids, 348, 118422.

Abstract. Disodium lauryl sulfosuccinate (diSLSS) is an anionic surfactant, wherein a dodecyl chain and sodium sulfosuccinate are ester-bonded.

Bährle-Rapp, M. (2007). Disodium Lauryl Sulfosuccinate. In Springer Lexikon Kosmetik und Körperpflege (pp. 168-168). Springer, Berlin, Heidelberg.

Tyagi, V. K. (2006). Sulfosuccinates as mild surfactants. Journal of Oleo Science, 55(9), 429-439.

Abstract.  This paper attempts to review the chemistry, types, synthesis, properties and distinguishing features of sulfosuccinates. The various applications of sulfosuccinate type anionic surfactants have also been discussed in detail.

Korting HC, Lukacs A, Hamm D, Stanzl K, Braun-Falco O. In-use tolerability of two new syndet bars with sodium cocoyl isethionate, disodium lauryl sulfosuccinate and wheat starch as major ingredients in differing relations: results of a cross-over trial. Int J Cosmet Sci. 1992 Dec;14(6):277-82. doi: 10.1111/j.1467-2494.1992.tb00060.x. 

Abstract. Synopsis In a cross-over trial two different new syndet bars differing in their content of sodium cocoyl isethionate, disodium lauryl sulfosuccinate and wheat starch as major components were compared in the cleansing of hand skin of 72 healthy volunteers.

Gao, Y., Yang, X., Bai, L. et al. Preparation and Physiochemical Properties of Disodium Lauryl Glucoside Sulfosuccinate. J Surfact Deterg 17, 603–608 (2014). https://doi.org/10.1007/s11743-013-1561-2

Abstract. A new synthetic route to a mild surfactant disodium lauryl glucoside sulfosuccinate (AG-SS) containing two hydrophilic groups is described and its measured physicochemical properties reported.

Disodium lauryl sulfosuccinate is a chemical compound whose hydrophilic groups are sulphonic acid and carboxylic acid.

It occurs in the form of a fine white powder, when heated to 70°C it becomes a transparent liquid.

What it is used for and where

Chemical raw material. Sulphosuccinates are the sodium salts of the alkyl ester of sulphosuccinic acid and make up approximately 49% of all anionic surfactants.

Cosmetics

It is an anionic surfactant that produces rich, fine foam that is easy to wash out without greasy effects. Compatible with other surfactants whose irritative effect it tends to reduce. Performs its function even in hard water. Widely used in the preparation of liquid soaps, foam cleansing creams, foam cleansers, foam shaving creams, shower gels.

Also used to improve skin elasticity, absorb ultraviolet rays, limit melanin synthesis, reduce pigment deposition.

Raw material for amide surfactants.

Usage: 4-10% in shampoo and 4-8% in bath foam. 0.5-5% in cosmetics (PH value should be below 7)

Other uses

Coatings, textiles, paper, leather and oil exploration industries.

Disodium lauryl sulfosuccinate studies

Typical commercial product characteristics Disodium lauryl sulfosuccinate

• Molecular Formula  C₁₇H₃₀Na₂O₇S   C₁₂H₂₅OOCCH₂CH(SO₃Na)COONa   C₁₆H₂₈Na₂O₇S   
• Molecular Weight     776.9
• CAS  19040-44-9
• UNII    H79W63DF3X
• EC Number   606-212-5
• DSSTox Substance ID  
• IUPAC  disodium;4-dodecoxy-4-oxo-3-sulfobutanoate
• InChI=1S/2C16H30O7S.2Na/c2*1-2-3-4-5-6-7-8-9-10-11-12-23-16(19)14(13-15(17)18)24(20,21)22;;/h2*14H,2-13H2,1H3,(H,17,18)(H,20,21,22);;/q;;2*+1/p-2  
• InChl Key      KHIQYZGEUSTKSB-UHFFFAOYSA-L
• SMILES   CCCCCCCCCCCCOC(=O)C(CC(=O)[O-])S(=O)(=O)O.CCCCCCCCCCCCOC(=O)C(CC(=O)[O-])S(=O)(=O)O.[Na+].[Na+]
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Synonyms:

• Butanedioic acid, 2-sulfo-, 1-dodecyl ester, sodium salt (1:2)
• Disodium dodecyl alpha-sulfosuccinate
• Sodium monododecyl sulfosuccinate
• disodium;4-dodecoxy-4-oxo-3-sulfobutanoate