Faex Extract/Yeast extract is a natural ingredient, a complex mixture of yeast extract.

The name defines the structure of the molecule:

• Faex is the Latin word for yeast.
• Extract refers to the substance obtained from a plant or other matter using a particular method.
• Yeast. Yeast is a type of fungus that is used in brewing and brewing. In the context of ingredients, yeast extract is a rich source of B vitamins and is often used as a flavor enhancer in foods. It is also used in cosmetics due to its skin conditioning properties.

The synthesis process takes place in several stages:

• Yeast cultivation. The yeast is grown in a controlled environment so that the yeast can grow and multiply.
• Collection. Once the yeast has reached the desired growth phase, it is collected by centrifugation by separating the yeast cells from the growth medium.
• Autolysis. The collected yeast cells are broken down into a process called autolysis. This involves treating the yeast with enzymes that break down the cell walls, releasing the cell contents.
• Separation. The autolyzed yeast mixture is separated into its component parts by processes such as centrifugation or filtration, which separate the soluble yeast extract from the walls of insoluble yeast cells.
• Concentration. The yeast extract is concentrated, by evaporation, to produce a dense and pasty substance.
• Quality control test. The final product is tested to ensure it meets the required specifications. This may involve testing the taste, color and other physical and chemical properties.

It appears as a yellowish or whitish powder with a characteristic odour, deliquescent, water-soluble with an acid reaction pH 6.6

What it is used for and where

Synthesis of high-protein intermediate materials consisting of bacterial growth factors and vitamins.

Food

It improves the taste of food products, softens dough and product, covers up intense flavour, too salty taste and adds a discrete aroma. Typically, fermentation for food products makes use of API, VC, Saccharomyces cerevisiae, amino acids and antibiotics, and makes use of modern biotechnology that biodegrades the nucleic acid and proteins in fresh yeast cells. The end product is free of fatty acids and cholesterol. Microbial culture medium: Bacillus subtilis, yeast and Mycoplasma, Gluconobacter, Acetobacter, Pseudomonas and others.

Dosages: 1.0-1.2% for baked bread, 0.3-0.5% for other products. Fermentation at 35 ~ 38°C.

Cosmetics

In Faex extract, there are peptides, amino acids, vitamins (often vitamin B1 thiamine and B vitamins) that have the function of moisturising and reactivating the skin.

Skin protectant. It creates a protective barrier on the skin to defend it from harmful substances, irritants, allergens, pathogens that can cause various inflammatory conditions. These products can also improve the natural skin barrier and in most cases more than one is needed to achieve an effective result.

Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.

Other uses

Biological compound for biochemical research

Industry

It is obtained, by enzymolysis, from the separation of fresh brewer's yeast emulsion. It contains trace elements, peptides, nucleotides, B vitamins and favourable environments for the growth of microorganisms.

Fermentation

Depending on its uses, Faex extract can be refined by the following fermentation processes:

• Refined product with high nitrogen concentration
• Refined product with low nitrogen concentration
• Refined product to pharmaceutical standards

For more information:

Faex Extract studies

Typical commercial product characteristics Bulk Yeast Extract

• Molecular Formula    C₁₉H₁₄O₂
• Molecular Weight      319.193
• Exact Mass    318.025543
• CAS  8013-01-2
• UNII    
• EC Number   232-387-9
• DSSTox Substance ID  DTXSID4051247
• IUPAC  2-(11H-benzo[a]fluoren-11-yl)acetic acid
• InChl=1S/C19H14O2/c20-18(21)11-17-15-8-4-3-7-14(15)16-10-9-12-5-1-2-6-13(12)19(16)17/h1-10,17H,11H2,(H,20,21)
• InChl Key      GQNBDGXKDJSVGQ-UHFFFAOYSA-N
• SMILES   C1=CC=C2C(=C1)C=CC3=C2C(C4=CC=CC=C34)CC(=O)O
• MDL number  MFCD00132599
• PubChem Substance ID    
• ChEBI  174614
• eCl@ss       42040000
• NACRES  NA.85   
• RTECS   ZF6610000

Synonyms

• Benzeneacetic acid, α-(2-bromoethyl)-α-phenyl-
• 4-bromo-2,2-diphenylbutanoic acid
• microbial growth medium
• Select Yeast Extract
• 4-Bromo-2,2-diphenylbutyric acid
• 2-(11H-benzo[a]fluoren-11-yl)acetic acid

Compendium of the most significant studies with reference to properties, intake, effects.

Kantayos V, Kim JS, Baek SH. Enhanced Anti-Skin-Aging Activity of Yeast Extract-Treated Resveratrol Rice DJ526. Molecules. 2022 Mar 17;27(6):1951. doi: 10.3390/molecules27061951.

Abstract. Resveratrol is a powerful antioxidant that defends against oxidative stress in cells but is not found in large quantities in plants. Resveratrol-enriched rice DJ526, which was developed as a functional crop, shows a diverse range of biological activities. Resveratrol production is measured as total resveratrol and its glycoside, piceid, which is mainly found in plant-derived resveratrol. In the present study, elicitation using yeast extract (YE), methyl jasmonate, and jasmonic acid increased resveratrol production in DJ526 rice seeds. DJ526 seeds elicited using 1 g/L (YE1) and 5 g/L yeast extract (YE5) showed enhanced resveratrol production and antioxidant activity. YE5-treated DJ526 seeds showed decreased melanin content by 46.1% and 37.0% compared with the negative control and DJ526 (non-elicitation), respectively. Both YE1 and YE5 efficiently improved the wound-healing activity by reducing the wound gap faster than in untreated cells, with a maximum rate of 60.2% at 24 h and complete closure at 48 h. YE1 and YE5 significantly decreased the levels of proinflammatory cytokine, TNF-α, and enhanced collagen synthesis in inflammatory cells. These findings indicate that YE-treated resveratrol rice DJ526 may improve resveratrol production and could be an active antiaging ingredient for cosmetic and skin therapy applications.

Tanguler, H., & Erten, H. (2008). Utilisation of spent brewer's yeast for yeast extract production by autolysis: The effect of temperature. Food and bioproducts processing, 86(4), 317-321.

Abstract. In this study, autolysis was induced by incubating cell suspensions of spent brewer's yeast at elevated temperatures of 45, 50, 55 and 60 °C with a reaction time ranging from 8 to 72 h. Contents and yields of solid, α-amino nitrogen, protein and carbohydrate were determined. It can be said that optimum temperature and time for the production of yeast extract was 50 °C for 24 h on the basis of α-amino nitrogen and protein contents. Sensory analysis was also done by yeast extract powder and control and samples with the addition of 0.5 and 1.0% yeast extract had the highest overall acceptance.

Bährle-Rapp, M. (2007). Faex Extract. In Springer Lexikon Kosmetik und Körperpflege (pp. 199-199). Springer, Berlin, Heidelberg.

Bährle-Rapp, M. (2007). Lactis Faex. In Springer Lexikon Kosmetik und Körperpflege (pp. 308-308). Springer, Berlin, Heidelberg.