Octenidine HCL is a chemical compound-

It appears as a white powder or in crystalline flakes.

What it is used for and where

Cationic surfactant active against Gram-positive and Gram-negative bacteria.

Medical

Octenidine HCL is an antiseptic of relatively recent conception that has shown its utility in wound treatment, abdominal lavage, and to the extent of 1% as a scolonising agent in liver tissue (1). It has been used as a nasal decolonising gel for Staphylococcus aureus nasal decolonisation although mupirocin and neomycin have proved more effective (2).

Cosmetics

Antimicrobial agent. This ingredient is able to suppress or inhibit the growth and replication of a broad spectrum of microorganisms such as bacteria, fungi and viruses by making the stratum corneum temporarily bactericidal and fungicidal.

• Molecular Formula  C₃₆H₆₄Cl₂N₄   
• Molecular Weight  623.8    
• CAS  70775-75-6
• UNII    U84956NU4B
• EC Number  274-861-8 

Synonyms:

• Octenidine dihydrochloride

References_____________________________________________________________________

(1) Arikan, Y., Akbulut, G., Sahin, D.A., Dilek, F.H., Saykol, V. and Dilek, O.N., 2007. Effects of octenidine HCl on liver tissue: Could it be an alternative scolicidal for hidatid disease?. World journal of surgery, 31, pp.1282-1285.

(2) Allport, J., Choudhury, R., Bruce-Wootton, P., Reed, M., Tate, D. and Malviya, A., 2022. Efficacy of mupirocin, neomycin and octenidine for nasal Staphylococcus aureus decolonisation: a retrospective cohort study. Antimicrobial Resistance & Infection Control, 11(1), pp.1-8.

Ariel, H., Kahn, A., Hila, Z.O., Anton, S., Natan, G. and Kolerman, R., 2022. A thermosensitive gel with an active hyaluronic acid ingredient that contains an octenidine preservation system as an adjunct to scaling and root planning: A randomized prospective clinical study. Clinical oral investigations, pp.1-13.