Tetramethyl Acetyloctahydronaphthalenes, also known as Iso E Super, is a synthetic fragrance ingredient used in the cosmetic and personal care industry. This compound is prized for its distinctive, long-lasting woody and amber-like scent, which enhances the olfactory profile of various products.

Chemical Composition and Structure
Tetramethyl Acetyloctahydronaphthalenes belong to the family of synthetic fragrance compounds. The chemical structure includes multiple methyl groups and a naphthalene core, which contribute to its unique scent profile. The compound can exist in different isomeric forms, providing a range of scent nuances.

Molecular Formula: C16H26O
Key Functional Groups: Acetyl and methyl groups attached to an octahydronaphthalene core.
Physical Properties
Tetramethyl Acetyloctahydronaphthalenes typically appear as a clear, colorless to pale yellow liquid. It is known for its high stability and persistence, which make it a valuable ingredient in perfumes and other fragranced products. The compound has a relatively low volatility, contributing to its long-lasting scent.

Cosmetic and Personal Care Applications
Fragrance: Tetramethyl Acetyloctahydronaphthalenes are primarily used as a fragrance ingredient in perfumes, colognes, and scented products. Its woody, amber-like scent adds depth and complexity to fragrance compositions.

Scent Fixative: Due to its long-lasting nature, it helps fix other volatile fragrance ingredients, enhancing the overall longevity of the scent.

Scent Modifier: It can modify and harmonize other fragrance notes, creating a balanced and appealing fragrance profile.

Deodorant: It can be used in deodorant formulations to mask unpleasant odors and provide a pleasant fragrance.

Environmental and Safety Considerations

Tetramethyl Acetyloctahydronaphthalenes are generally considered safe for use in cosmetic and personal care products when used within recommended concentrations. It is important to follow regulatory guidelines and safety assessments to ensure consumer safety. The production and use of this compound should also consider environmental impact and sustainability practices.

Cosmetic Safety

Restricted cosmetic ingredient as III/344 a Relevant Item in the Annexes of the European Cosmetics Regulation 1223/2009. Substance or ingredient reported: 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl- 2-naphthyl)ethan- 1-one; 1-(1,2,3,4,5,6,7,8-octahydro-2,3,5,5-tetramethyl- 2-naphthyl)ethan- 1-one; 1-(1,2,3,5,6,7,8,8a- octahydro-2,3,8,8-tetramethyl- 2-naphthyl)ethan- 1-one; 1-(1,2,3,4,6,7,8,8a- octahydro-2,3,8,8-tetramethyl- 2-naphthyl)ethan- 1-one. The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Cosmetics - INCI Functions


Fragrance. It plays a very important role in the formulation of cosmetic products as it provides the possibility of enhancing, masking or adding fragrance to the final product, increasing its marketability. It is able to create a perceptible pleasant odour, masking a bad smell. The consumer always expects to find a pleasant or distinctive scent in a cosmetic product.

Perfuming. Unlike fragrance, which can also contain slightly less pleasant or characteristic odours, the term perfume indicates only very pleasant fragrances. Used for perfumes and aromatic raw materials.

Skin conditioning agent - Miscellaneous. This ingredient has the task of modifying and improving the condition of the skin when it is damaged or dry, reducing flaking and restoring its elasticity.
Synonyms:

CAS: 54464-57-2 54464-59-4 68155-66-8 68155-67-9 EC number 259-174-3 259-175-9 268-978-3 268-979-9